Berberine: Is it a safe, natural Ozempic alternative – or just another TikTok fad?

The expert advice is to exercise caution with it – in addition to consulting your GP or other medical professional before trying it, because it hasn’t been scrutinised in the same way controlled medicines have.

“Berberine hasn’t been developed as a proper drug, so we don’t know the right dose or the optimal dose in the safety range in the way we do with other drugs. All those other drugs go through rigorous testing to make sure they’re safe and we know what’ll happen with a certain dose of the drug,” Prof. Shephard said.

“With Berberine, it’s uncontrolled because it’s a natural substance. So, you know, my worry is that some people will think ‘more is better’ when actually they could be doing themselves damage by taking too much.” 

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