Weight-loss injections ‘could cause frailty without exercise’

Patients using weight-loss injections risk losing dangerous levels of muscle and becoming frail unless they also take up exercise, doctors have warned.

The drugs work by suppressing the appetite, but in some patients this sudden drop in food intake causes healthy muscle and bone mass to “waste away”. Semaglutide, known by brand names Wegovy and Ozempic, is being given to tens of thousands of obese patients in the UK via the NHS and private clinics.

While the “miracle” weekly injections are being hailed as a solution to the obesity epidemic, there are mounting fears people are using them as a quick fix, without proper support.

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Those taking the weight-loss drugs are being urged to increase

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